The Psilocybin Record
Record / Nov 2026 / Clinical trials

Psilocybin clinical trials

Could you join one? Most of the 343 registered trials are not taking new participants. 140 of them are in the recruiting stage, and your condition is the fastest way to search them. Trial starts have grown roughly seven-fold since 2019.

Sources: ClinicalTrials.gov, EU CTIS, ISRCTN, and ANZCTR · updated 9 Nov 2026 · 343 records

Registry data is reported by sponsors and shown as filed.

ClinicalTrials.gov data courtesy of the U.S. National Library of Medicine.

Where the trials run

61 places host psilocybin trials. Every place links to its legal record.

Show all 61 places

Recruiting now

The recruiting stage holds 140 trials across 17 countries: 100 are enrolling now, 35 are not yet recruiting, and 5 enroll by invitation only. 123 of them name a study contact on the record.

Recruiting trials, and how to join →

Trial eligibility is determined solely by each study team. Verify details on the official registry record before acting.

Find a trial

Filter by condition, status, country, and stage. Each title opens the trial’s own registry page, where the eligibility rules are spelled out in full.

Depression

125 trials · 48 in the recruiting stage
Does it work?Not yet recruiting
Psilocybin FCR Early-Stage Breast Cancer
NCT07909408Phase 2n=100United Statesupdated Nov 2026

Ages 21 and upfemale onlypatients onlystudy contact listed

Does it work?Not yet recruiting
Psilocybin for Depression in Veterans
NCT07895134Phase 2n=150United Statesupdated Oct 2026

Ages 18 to 70all sexespatients onlystudy contact listed

Does it work?Not yet recruiting
Group PACBT for Depression
NCT07566104Phase 2n=30United Statesupdated May 2026

Ages 21 to 60all sexespatients only

Safety & dosingNot yet recruiting
MLS101 Study in PMDD
NCT07818720Phase 1n=32updated Nov 2026

Ages 18 to 50female onlypatients onlystudy contact listed

PTSD & trauma

22 trials · 11 in the recruiting stage
Does it work?Recruiting
Psilocybin-Assisted Therapy
NCT07332143Phase 2n=150United Statesupdated Oct 2026

Ages 18 and upall sexespatients onlystudy contact listed

Safety & dosingRecruiting
Psilocybin for Prolonged Grief Disorder
NCT06724289Early phase 1n=12United Statesupdated Jun 2026

Ages 18 to 65all sexeshealthy volunteers acceptedstudy contact listed

Addiction

46 trials · 20 in the recruiting stage

Anxiety

6 trials · 2 in the recruiting stage

Cancer & end of life

17 trials · 7 in the recruiting stage
Does it work?Recruiting
Psilocybin Therapy in Advanced Cancer
NCT05398484Phase 2 / Phase 3n=200United Statesupdated Oct 2026

Ages 21 to 100all sexespatients onlystudy contact listed

OCD

10 trials · 3 in the recruiting stage
Does it work?Not yet recruiting
Psilocybin for Treatment of OCD-2
NCT06992999Phase 1 / Phase 2n=20United Statesupdated May 2026

Ages 18 and upall sexespatients onlystudy contact listed

Eating disorders

10 trials · 3 in the recruiting stage

Pain & headache

19 trials · 8 in the recruiting stage

Neurological

14 trials · 5 in the recruiting stage

Other conditions

16 trials · 9 in the recruiting stage
Does it work?Recruiting
Mindfulness-Assisted Psychedelic Therapy
NCT06233344Phase 2n=40United Statesupdated Aug 2026

Ages 25 and upall sexeshealthy volunteers acceptedstudy contact listed

Healthy & mechanism

58 trials · 24 in the recruiting stage
Safety & dosingRecruiting
The ENHANCE Study: taVNS and Psilocybin
NCT05866471Phase 1n=115United Statesupdated Oct 2026

Ages 18 to 70all sexeshealthy volunteers acceptedstudy contact listed

Free monthly email

Track changes to psilocybin law.

Clinical trials, bills, and ballot measures across the world: one free email a month with what changed.

New trials and status changes arrive most months. One email when they do.

No spam. Never shared. Unsubscribe anytime. Privacy statement

The law won’t email you. We will.

Common questions

Can I join a trial?
140 trials are in the recruiting stage; 97 of them list sites this register can place. There is no central application: each registry record carries its own eligibility bounds and, where the sponsor filed one, a study contact. 123 of the recruiting trials name a study contact on the record. You contact that team, screening follows, and consent is signed before enrollment. Eligibility is decided by each study team.
Is there a trial for my condition?
Depression is the most studied condition with 125 trials, then addiction with 56, PTSD with 31, and pain with 26. A trial studying more than one condition is counted under each. Every condition is a filter in the register above.
Where are the results?
The register records status, not verdicts. Of 97 completed trials, 22 have results posted to the registry and 5 name a published results paper. A further 59 have papers that cite the trial without reporting its results, and 11 have nothing on record. We count a trial as having results only where the registry says so.
Trials run in places where psilocybin is illegal. How?
Clinical trials operate under research authorizations that are separate from a place’s general law. The atlas above links every place to its legal record on this site.
What do the phases mean?
Phase 1 tests safety and dosing. Phases 2 and 3 test whether the treatment works against comparison groups; 174 trials here are in phase 2 or 3. No psilocybin trial has reached phase 4, the after-approval stage.
Is the field growing?
Trial starts have grown roughly seven-fold since 2019: 8 started in 2019, 59 in 2025, and 74 are already listed for 2026. Start dates include scheduled starts from the registries.
Where does this data come from?
ClinicalTrials.gov, the EU CTIS, ISRCTN, and ANZCTR, refreshed on a weekly cadence. ClinicalTrials.gov data is courtesy of the U.S. National Library of Medicine. The corpus behind this page was last updated 9 Nov 2026.

Every figure here is counted from the register at build time. This site makes no medical claims about psilocybin.