Tennessee
Psilocybin is illegal in Tennessee as of 16 Aug 2026.1
- Corrected and re-checked against 2 cited sources at this review.
1. What the law is
Nobody filed a psilocybin bill in Tennessee's 114th General Assembly. The psychedelics law the state did pass concerns a different drug: the HOPE Treatment Act, SB 2149 substituted for HB 2075, signed by the Governor on 22 May 2026 and filed as Public Chapter 1119. It adds a new Chapter 16 to Title 53 encouraging Tennessee research institutions to join federally authorized ibogaine clinical trials for opioid use disorder and other conditions. Nothing happens under it until the FDA authorizes a trial.
Psilocybin is illegal in Tennessee. It is classified as a Schedule I controlled substance under Tennessee Code Annotated § 39-17-406, the state's controlled-substances scheduling statute, which lists psilocybin and psilocyn among Schedule I hallucinogenic substances. Simple possession is a Class A misdemeanor under Tenn. Code Ann. § 39-17-418, punishable by up to 11 months and 29 days in jail and a fine of up to $2,500, while manufacture, delivery, or sale is prosecuted as a felony under Tenn. Code Ann. § 39-17-417. Tennessee has no law authorizing medical, therapeutic, or supervised use of psilocybin.
Psilocybin remains a Schedule I substance in Tennessee with no legal pathway for personal, medical, or supervised use as of June 2026. In the 2026 session, the General Assembly passed the HOPE Treatment Act (HB 2075 / SB 2149), enacted as Public Chapter 1119 and signed by Governor Bill Lee on May 22, 2026; that act authorizes Tennessee hospitals and qualified research facilities to participate in FDA-authorized clinical trials involving ibogaine and is itself contingent on federal investigational-new-drug authorization. The HOPE Treatment Act concerns ibogaine, not psilocybin, and does not change psilocybin's Schedule I status or create any legal access to psilocybin. No psilocybin-specific legislation advanced in the 2026 session, and neither decriminalization nor any regulated-access framework for psilocybin exists in Tennessee.
2. Pending legislation
None located. The General Assembly's own advanced bill search returns no bill containing the term psilocybin in the 114th General Assembly, searched 16 Aug 2026. The ibogaine HOPE Treatment Act is enacted rather than pending: Public Chapter 1119, signed 22 May 2026.
3. History
The laws behind today’s status, when each took effect, and every review since, in order.
The Tennessee General Assembly advances the HOPE Treatment Act (HB 2075 / SB 2149), an ibogaine clinical-trial research framework; the bill does not address psilocybin.
Governor Bill Lee signs the HOPE Treatment Act into law as Public Chapter 1119, authorizing participation in FDA-authorized ibogaine clinical trials and leaving psilocybin's Schedule I status unchanged.
Tennessee's entry now records that the ibogaine HOPE Treatment Act was signed on 22 May 2026 and became Public Chapter 1119. It does not concern psilocybin, whose status is unchanged.
Psilocybin remains a Schedule I controlled substance under Tenn. Code Ann. § 39-17-406, with no psilocybin-specific legislation enacted in the 2026 session.
Tennessee had been recorded as mixed on the basis of a law that names only ibogaine. No psilocybin legislation exists in the state, so the status was corrected to illegal.
4. Trials in Tennessee
Interventional psilocybin trials with at least one study site in Tennessee, drawn from ClinicalTrials.gov, EU CTIS, and ISRCTN. Registry data is reported by sponsors and shown as filed.
Recruiting, active, completed and closed add up to the 2 trials with a study site in Tennessee, as of Aug 2026. Closed covers trials terminated, suspended, withdrawn or left unverified.
| Registry ID | Trial | Phase | Sponsor | Status | Started |
|---|---|---|---|---|---|
| NCT06605105 (opens in new tab) | Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND) (opens in new tab)Site at Clinical Neuroscience Solutions, CNS Healthcare, Memphis | Phase Phase 3 | Sponsor Cybin IRL Limited | Status Enrolling by invitation | Started |
| NCT06564818 (opens in new tab) | A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder (opens in new tab)Site at Clinical Neuroscience Solutions, CNS Healthcare, Memphis | Phase Phase 3 | Sponsor Cybin IRL Limited | Status Active, not recruiting | Started |
ClinicalTrials.gov data courtesy of the U.S. National Library of Medicine.
5. Common questions
Is psilocybin legal in Tennessee?
No. Psilocybin is illegal in Tennessee, where it is classified as a Schedule I controlled substance under Tennessee Code Annotated § 39-17-406. There is no medical, therapeutic, or decriminalized exception under Tennessee law.
What are the penalties for psilocybin possession in Tennessee?
Simple possession of psilocybin is a Class A misdemeanor under Tenn. Code Ann. § 39-17-418, punishable by up to 11 months and 29 days in jail and a fine of up to $2,500. Manufacture, delivery, or sale is charged as a felony under Tenn. Code Ann. § 39-17-417, with penalties that increase based on quantity.
Did the 2026 HOPE Treatment Act legalize psilocybin in Tennessee?
No. The HOPE Treatment Act (HB 2075 / SB 2149), enacted as Public Chapter 1119 and signed on May 22, 2026, authorizes Tennessee facilities to participate in FDA-authorized clinical trials involving ibogaine. It does not mention or apply to psilocybin and does not change psilocybin's Schedule I status.
Is psilocybin decriminalized anywhere in Tennessee?
No. No Tennessee city or county has decriminalized psilocybin, and the state has not enacted any measure deprioritizing enforcement. Psilocybin remains a Schedule I controlled substance statewide under Tenn. Code Ann. § 39-17-406.
Are magic mushrooms ("shrooms") legal in Tennessee?
"Magic mushrooms" and "shrooms" are common names for fungi that contain psilocybin. Psilocybin is illegal in Tennessee as of 16 Aug 2026. Some laws control the compound and the fungus separately, so this record states the position for psilocybin in Tennessee.
Sources and confidence
Every status line is checked against the primary sources below. How each record is graded for confidence is set out in the methodology.
- 1.wapp.capitol.tn.gov (opens in new tab) · wapp.capitol.tn.gov
- 2.nashvillebanner.com (opens in new tab) · nashvillebanner.com
Cited at the review
This information is for educational purposes only and does not constitute legal advice. Laws change frequently, and enforcement practice can differ from the letter of the law. Verify current status with local authorities before relying on this record.
Changes to this record
Every change we have made to this record, dated, corrections included. Nothing changes silently.
Tennessee had been recorded as mixed on the basis of a law that names only ibogaine. No psilocybin legislation exists in the state, so the status was corrected to illegal.
Tennessee's entry now records that the ibogaine HOPE Treatment Act was signed on 22 May 2026 and became Public Chapter 1119. It does not concern psilocybin, whose status is unchanged.
Tennessee: psilocybin legal status. The Psilocybin Record. Accession US-TN-001. Status as of 16 Aug 2026. https://psilocybinlegalization.com/record/tennessee
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