Alabama
Psilocybin is illegal in Alabama as of 18 Aug 2026.1
- Checked against 2 cited sources at this review.
1. What the law is
Ala. Code § 20-2-23(b)(3) (Schedule I: Psilocybin, Psilocyn); Ala. Admin. Code 420-7-2 App. A (official Controlled Substances List)1
Alabama lists psilocybin and psilocyn in Schedule I at Ala. Code 20-2-23(b)(3). The state has enacted no change to that as of 2026.
Both psilocybin and psilocyn are named in Alabama's Schedule I, at Alabama Code Section 20-2-23(b)(3)(o)-(p). That is the most restrictive tier the Alabama Uniform Controlled Substances Act provides, and possession, manufacture, sale and distribution are criminal offenses under it. Alabama law carves out no medical, therapeutic or decriminalized use, and the legislature had enacted no such measure as of 2026.
Psilocybin's Schedule I status in Alabama derives from the Alabama Uniform Controlled Substances Act (Title 20, Chapter 2 of the Code of Alabama), which mirrors the federal Controlled Substances Act in placing psilocybin and psilocyn among substances the legislature has classified as having high abuse potential and no accepted state-recognized use. As of 2026, the Alabama Legislature has enacted no bill to decriminalize, reschedule, or create a regulated-access program for psilocybin, and no psilocybin study task force, pilot program, or therapeutic-access framework exists under Alabama law. No trigger law or contingent statute is in effect, so the substance remains fully prohibited; any future change would require new legislation passed by the Alabama Legislature. Searches of the 2024, 2025, and 2026 regular sessions identify no psilocybin reform measure advancing through the legislature.
2. Pending legislation
No bill is on file in Alabama that would change this record, as of the 18 Aug 2026 review.
3. History
The laws behind today’s status, when each took effect, and every review since, in order.
Alabama enacts the Alabama Uniform Controlled Substances Act (Title 20, Chapter 2, Code of Alabama), establishing the state's controlled-substance schedules.
Psilocybin and psilocyn remain Schedule I controlled substances under Alabama Code Section 20-2-23; no psilocybin reform legislation has been enacted.
4. Trials in Alabama
Interventional psilocybin trials with at least one study site in Alabama, drawn from ClinicalTrials.gov, EU CTIS, and ISRCTN. Registry data is reported by sponsors and shown as filed.
Recruiting, active, completed and closed add up to the 8 trials with a study site in Alabama, as of Aug 2026. Closed covers trials terminated, suspended, withdrawn or left unverified.
| Registry ID | Trial | Phase | Sponsor | Status | Started |
|---|---|---|---|---|---|
| NCT07774702 (opens in new tab) | Psilocybin for Methamphetamine Use Disorder (opens in new tab)Site at University of Alabama at Birmingham, Birmingham | Phase Phase 2 | Sponsor Peter Hendricks | Status Not yet recruiting | Started |
| NCT07226232 (opens in new tab) | Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression (opens in new tab)Recruiting in Birmingham and Tuscaloosa | Phase Phase 3 | Sponsor VA Office of Research and Development | Status Recruiting | Started |
| NCT06793397 (opens in new tab) | A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder (opens in new tab)Recruiting at UAB Psychiatry and Behavioral Neurology, Birmingham | Phase Phase 3 | Sponsor Cybin IRL Limited | Status Recruiting | Started |
| NCT05068791 (opens in new tab) | Psilocybin-facilitated Treatment for Chronic Pain (opens in new tab)Recruiting at UAB Beacon Tower, Birmingham | Phase Phase Early 1 | Sponsor University of Alabama at Birmingham | Status Recruiting | Started |
| NCT05452772 (opens in new tab) | 5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder (opens in new tab)Recruiting at University of Alabama at Birmingham, Birmingham | Phase Phase 2 | Sponsor Johns Hopkins University | Status Recruiting | Started |
| NCT06308653 (opens in new tab) | Psilocybin for Major Depressive Disorder (MDD) (opens in new tab)Site at University of Alabama Clinical Research Unit, Birmingham | Phase Phase 3 | Sponsor Usona Institute | Status Active, not recruiting | Started |
| NCT05227742 (opens in new tab) | Exploratory Study of Low Dose Psilocybin (opens in new tab)Site at University of Alabama at Birmingham, Birmingham | Phase Phase Early 1 | Sponsor University of Alabama at Birmingham | Status Withdrawn | Started |
| NCT02037126 (opens in new tab) | Psilocybin-facilitated Treatment for Cocaine Use (opens in new tab)Site at UAB Outpatient Clinical Research Unit, Birmingham | Phase Phase 2 | Sponsor University of Alabama at Birmingham | Status Completed | Started |
ClinicalTrials.gov data courtesy of the U.S. National Library of Medicine.
5. Common questions
Is psilocybin legal in Alabama?
No. Psilocybin is illegal in Alabama. It and its metabolite psilocyn are listed as Schedule I controlled substances under Alabama Code Section 20-2-23, and no state law authorizes medical, therapeutic, or recreational use.
What is the penalty for psilocybin possession in Alabama?
Because psilocybin is a Schedule I controlled substance, possession is prosecuted as unlawful possession of a controlled substance under the Alabama Uniform Controlled Substances Act (Title 20, Chapter 2, Code of Alabama). Manufacture, sale, and distribution are separately charged offenses. Specific charges and sentencing depend on the conduct and quantity; consult the controlling statutes or a licensed attorney for case-specific exposure.
Has Alabama decriminalized psilocybin?
No. Alabama has not decriminalized psilocybin. As of 2026, the Alabama Legislature has enacted no measure to decriminalize, reschedule, or deprioritize enforcement of psilocybin offenses, and the substance remains a Schedule I controlled substance under Alabama Code Section 20-2-23.
Does Alabama have a psilocybin therapy or medical-access program?
No. No Alabama statute authorizes supervised, medical, or therapeutic psilocybin use, and no study task force or pilot program has been established under state law. Any such program would require new legislation enacted by the Alabama Legislature.
Are magic mushrooms ("shrooms") legal in Alabama?
"Magic mushrooms" and "shrooms" are common names for fungi that contain psilocybin. Psilocybin is illegal in Alabama as of 18 Aug 2026. Some laws control the compound and the fungus separately, so this record states the position for psilocybin in Alabama.
Sources and confidence
Every status line is checked against the primary sources below. How each record is graded for confidence is set out in the methodology.
- 1.adfs.alabama.gov (opens in new tab) · adfs.alabama.gov
- 2.codes.findlaw.com (opens in new tab) · codes.findlaw.com
Cited at the review
This information is for educational purposes only and does not constitute legal advice. Laws change frequently, and enforcement practice can differ from the letter of the law. Verify current status with local authorities before relying on this record.
Changes to this record
Every change we have made to this record, dated, corrections included. Nothing changes silently.
Nothing has needed correcting or updating since this record first published.
Alabama: psilocybin legal status. The Psilocybin Record. Accession US-AL-001. Status as of 18 Aug 2026. https://psilocybinlegalization.com/record/alabama
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