Indiana
Psilocybin is illegal in Indiana as of 16 Aug 2026.1
- Corrected and re-checked against 2 cited sources at this review.
1. What the law is
HB 1259 (2024), Public Law 152-2024, signed March 13, 2024: establishes the therapeutic psilocybin research fund, administered by the division of mental health and addiction. The biennial state budget, HB 1001 (2025), Public Law 213-2025, signed May 6, 2025, appropriated $300,000 in each year of the 2025-2027 biennium, $600,000 in total, from the State Unrestricted Opioid Settlement Account (IC 4-12-16.2-5(1)) rather than the state general fund, and widened the account to ibogaine; it is now titled the therapeutic psilocybin and ibogaine research fund at IC 12-21-9-4, with 'ibogaine' defined at IC 12-21-9-1.5. Research funding only; psilocybin remains Schedule I with no patient access program.1
Indiana pays for psilocybin research and gives nobody access to the drug. House Bill 1259 (2024), Public Law 152-2024, created a state therapeutic psilocybin research fund; the biennial state budget, House Bill 1001 (2025), Public Law 213-2025, put $600,000 into that fund across the two-year period, drawn on the state's opioid settlement account rather than general revenue, and widened it to ibogaine. The bill that would have opened a route, SB 173 (2026), would have let certain practitioners provide neuroplastogen treatment including psilocybin to qualified patients with life-threatening conditions. It was amended and reported do pass in January 2026, then stopped in the Committee on Appropriations. Possession is still a Schedule I offense.
Indiana Code 35-48-2-4 puts psilocybin in Schedule I, and possession, manufacture and delivery are all prosecuted as criminal offenses. No state program gives a patient a lawful route to the drug. The one recent piece of legislation, House Bill 1259 of 2024, set up a therapeutic psilocybin research fund; it pays for clinical research and leaves the prohibited status exactly where it was.
Psilocybin remains a Schedule I controlled substance in Indiana, and the recent legislative activity has not created any current legal access. House Bill 1259 (2024), signed March 13, 2024, established a therapeutic psilocybin research fund directing money to research institutions to study the compound and report findings to state health and mental-health agencies; a standalone appropriation bill, House Bill 1166 (2025), died in the Committee on Ways and Means with a last action of January 28, 2025, and the money instead reached the fund through the biennial state budget, House Bill 1001 (2025), Public Law 213-2025, which appropriated $300,000 in each year of the 2025-2027 biennium, $600,000 in total, drawn on the State Unrestricted Opioid Settlement Account rather than the state general fund. That same act widened the account to cover ibogaine, and it is now the therapeutic psilocybin and ibogaine research fund at Indiana Code 12-21-9-4. Lawmakers and the bill's sponsors stated publicly that the measure funds research and does not legalize psilocybin outside of clinical studies. Separately, Senate Bill 173 (2026), which would have permitted neuroplastogen treatment including psilocybin for patients with life-threatening conditions, was introduced on January 5, 2026, amended and reported do pass by the Committee on Health and Provider Services, and reassigned to the Committee on Appropriations on January 15, 2026, where it received no further action and died. As of the most recent review, possession of psilocybin outside an authorized research setting remains a criminal offense in Indiana.
2. Pending legislation
Introduced but not yet law. If a bill passes, this record changes with it.
SB 173 (2026), which would allow certain practitioners to provide neuroplastogen treatment, including psilocybin, to qualified patients with life-threatening conditions: amended, reported favorably do pass by the Committee on Health and Provider Services and reassigned to the Committee on Appropriations on January 15, 2026. The Indiana General Assembly's own bill record shows no action after that date, checked 16 August 2026.
3. History
The laws behind today’s status, when each took effect, and every review since, in order.
House Bill 1259 signed into law, creating a state therapeutic psilocybin research fund for clinical research; psilocybin remains Schedule I with no patient-access program.
Illegal status takes effect.
House Bill 1001, the biennial state budget, became Public Law 213-2025 and appropriated $300,000 a year, $600,000 across the biennium, to the fund established by HB 1259, drawn on the State Unrestricted Opioid Settlement Account. It also widened the fund to cover ibogaine. The standalone appropriation bill HB 1166 (2025) had died in committee.
Senate Bill 173 introduced to permit neuroplastogen treatment, including psilocybin, for life-threatening conditions.
Senate Bill 173 was amended, reported do pass, and reassigned to the Committee on Appropriations, where it received no further action and died.
Indiana had been marked mixed. The only thing the state has enacted is a research fund, which pays for studies and opens no route for patients, so the status is corrected to illegal.
Indiana's research fund was paid for by the biennial state budget, not by the standalone bill the entry credited, and the fund now covers ibogaine as well as psilocybin. Corrected from the legislature's own records.
Indiana's psilocybin research fund is funded at $300,000 a year, $600,000 over the two-year budget, and the money comes from the state's opioid settlement account rather than general tax revenue. The amount and its source are now recorded from the budget act itself.
4. Trials in Indiana
Interventional psilocybin trials with at least one study site in Indiana, drawn from ClinicalTrials.gov, EU CTIS, and ISRCTN. Registry data is reported by sponsors and shown as filed.
Recruiting, active, completed and closed add up to the 1 trial with a study site in Indiana, as of Aug 2026. Closed covers trials terminated, suspended, withdrawn or left unverified.
| Registry ID | Trial | Phase | Sponsor | Status | Started |
|---|---|---|---|---|---|
| NCT07499583 (opens in new tab) | Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder (opens in new tab)two sites in Indianapolis | Phase Phase 1/2 | Sponsor Indiana University | Status Not yet recruiting | Started |
ClinicalTrials.gov data courtesy of the U.S. National Library of Medicine.
5. Common questions
Is psilocybin legal in Indiana?
No. Psilocybin is a Schedule I controlled substance under the Indiana Controlled Substances Act, and possession, manufacture, and delivery are prohibited and prosecuted as criminal offenses. Indiana has no program providing patients legal access to psilocybin.
Does Indiana's psilocybin research fund mean psilocybin is legal?
No. House Bill 1259 (2024) created a fund supporting clinical research into psilocybin, and the biennial state budget, House Bill 1001 (2025), Public Law 213-2025, put money into it: $300,000 in each year of the 2025-2027 biennium, $600,000 in total, drawn on the State Unrestricted Opioid Settlement Account. The standalone bill HB 1166 (2025) that would have funded it died in committee. According to the bill's sponsors and state lawmakers, it funds research only and does not legalize psilocybin or create any patient-access program; the substance remains Schedule I.
What happened to Senate Bill 173 in Indiana?
Senate Bill 173 (2026) would have permitted neuroplastogen treatment, including psilocybin, for patients with life-threatening conditions. It was introduced on January 5, 2026, amended and reported do pass by the Committee on Health and Provider Services, then reassigned to the Committee on Appropriations on January 15, 2026, where it received no further action and died. Indiana law is unchanged.
Is possession of psilocybin a crime in Indiana?
Yes. Because psilocybin is classified as a Schedule I controlled substance under Indiana Code 35-48-2-4, possessing it outside an authorized research setting is a criminal offense under Indiana's controlled-substances laws.
Are magic mushrooms ("shrooms") legal in Indiana?
"Magic mushrooms" and "shrooms" are common names for fungi that contain psilocybin. Psilocybin is illegal in Indiana as of 16 Aug 2026. Some laws control the compound and the fungus separately, so this record states the position for psilocybin in Indiana.
Sources and confidence
Every status line is checked against the primary sources below. How each record is graded for confidence is set out in the methodology.
- 1.iga.in.gov (opens in new tab) · iga.in.gov
- 2.iga.in.gov (opens in new tab) · iga.in.gov
Cited at the review
This information is for educational purposes only and does not constitute legal advice. Laws change frequently, and enforcement practice can differ from the letter of the law. Verify current status with local authorities before relying on this record.
Changes to this record
Every change we have made to this record, dated, corrections included. Nothing changes silently.
Indiana's psilocybin research fund is funded at $300,000 a year, $600,000 over the two-year budget, and the money comes from the state's opioid settlement account rather than general tax revenue. The amount and its source are now recorded from the budget act itself.
Indiana's research fund was paid for by the biennial state budget, not by the standalone bill the entry credited, and the fund now covers ibogaine as well as psilocybin. Corrected from the legislature's own records.
Indiana had been marked mixed. The only thing the state has enacted is a research fund, which pays for studies and opens no route for patients, so the status is corrected to illegal.
Indiana: psilocybin legal status. The Psilocybin Record. Accession US-IN-001. Status as of 16 Aug 2026. https://psilocybinlegalization.com/record/indiana
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