1. What the law is
Indiana pays for psilocybin research and gives nobody access to the drug. One bill created a state research fund in 2024; the biennial budget filled it two years later, drawing on the state's opioid settlement account rather than general revenue, and widened it to ibogaine. The bill that would have opened a route, SB 173 (2026), would have let certain practitioners provide neuroplastogen treatment including psilocybin to qualified patients with life-threatening conditions. It was amended and reported do pass in January 2026, then stopped in the Committee on Appropriations. Possession is still a Schedule I offense.
Indiana Code 35-48-2-4 puts psilocybin in Schedule I, and possession, manufacture and delivery are all prosecuted as criminal offenses. No state program gives a patient a lawful route to the drug. The one recent piece of legislation, House Bill 1259 of 2024, set up a therapeutic psilocybin research fund; it pays for clinical research and leaves the prohibited status exactly where it was.
The fund directs money to research institutions to study the compound and report findings to state health and mental-health agencies. It nearly did not get any: a standalone appropriation bill, House Bill 1166 (2025), died in the Committee on Ways and Means with a last action of January 28, 2025, and the money reached the fund through the biennial budget instead. Senate Bill 173 (2026) was introduced on January 5, 2026 and reassigned to the Committee on Appropriations on January 15, 2026, where it received no further action.
2. Trials in Indiana
Interventional psilocybin trials with at least one site in Indiana, as their sponsors filed them with ClinicalTrials.gov, EU CTIS and ISRCTN. Each row links to the registry record, which sets out who may take part.
Recruiting or opening counts trials recruiting now, not yet recruiting, or enrolling by invitation. Closed counts trials terminated, suspended, withdrawn or left unverified by their sponsors.
| Registry ID | Trial | Phase | Sponsor | Status | Start date |
|---|---|---|---|---|---|
| NCT07499583 | Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder (opens in new tab)Two sites in Indianapolis | Phase Phase 1/2 | Sponsor Indiana University | Status Not yet recruiting | Start date |
ClinicalTrials.gov data courtesy of the U.S. National Library of Medicine.
3. History
The legal events behind this entry, dated and oldest first. Our own reviews and corrections are listed under Changes to this record.
House Bill 1259 signed into law, creating a state therapeutic psilocybin research fund for clinical research; psilocybin remains Schedule I with no patient-access program.
House Bill 1001, the biennial state budget, became Public Law 213-2025 and appropriated $300,000 a year, $600,000 across the biennium, to the fund established by HB 1259, drawn on the State Unrestricted Opioid Settlement Account. It also widened the fund to cover ibogaine. The standalone appropriation bill HB 1166 (2025) had died in committee.
Senate Bill 173 introduced to permit neuroplastogen treatment, including psilocybin, for life-threatening conditions.
Senate Bill 173 was amended, reported do pass, and reassigned to the Committee on Appropriations, where it received no further action and died.
4. Proposed laws
Proposals that are not yet law and would change this entry if adopted.
SB 173 (2026), which would allow certain practitioners to provide neuroplastogen treatment, including psilocybin, to qualified patients with life-threatening conditions: amended, reported favorably do pass by the Committee on Health and Provider Services and reassigned to the Committee on Appropriations on January 15, 2026. The Indiana General Assembly's own bill record shows no action after that date, checked 16 August 2026.
5. Common questions
Is psilocybin legal in Indiana?
No. Psilocybin is a Schedule I controlled substance under the Indiana Controlled Substances Act, and possession, manufacture, and delivery are prohibited and prosecuted as criminal offenses. Indiana has no program providing patients legal access to psilocybin.
Does Indiana's psilocybin research fund mean psilocybin is legal?
No. House Bill 1259 (2024) created a fund supporting clinical research into psilocybin, and the biennial state budget, House Bill 1001 (2025), Public Law 213-2025, put money into it: $300,000 in each year of the 2025-2027 biennium, $600,000 in total, drawn on the State Unrestricted Opioid Settlement Account. The standalone bill HB 1166 (2025) that would have funded it died in committee. According to the bill's sponsors and state lawmakers, it funds research only and does not legalize psilocybin or create any patient-access program; the substance remains Schedule I.
What happened to Senate Bill 173 in Indiana?
Senate Bill 173 (2026) would have permitted neuroplastogen treatment, including psilocybin, for patients with life-threatening conditions. It was introduced on January 5, 2026, amended and reported do pass by the Committee on Health and Provider Services, then reassigned to the Committee on Appropriations on January 15, 2026, where it received no further action and died. Indiana law is unchanged.
Is possession of psilocybin a crime in Indiana?
Yes. Because psilocybin is classified as a Schedule I controlled substance under Indiana Code 35-48-2-4, possessing it outside an authorized research setting is a criminal offense under Indiana's controlled-substances laws.
Are magic mushrooms ("shrooms") legal in Indiana?
"Magic mushrooms" and "shrooms" are common names for fungi that contain psilocybin, and this entry states the law on psilocybin itself, which some laws treat separately from the fungus. Psilocybin is illegal in Indiana.
Read the law
HB 1259 (2024), Public Law 152-2024, signed March 13, 2024: establishes the therapeutic psilocybin research fund, administered by the division of mental health and addiction. The biennial state budget, HB 1001 (2025), Public Law 213-2025, signed May 6, 2025, appropriated $300,000 in each year of the 2025-2027 biennium, $600,000 in total, from the State Unrestricted Opioid Settlement Account (IC 4-12-16.2-5(1)) rather than the state general fund, and widened the account to ibogaine; it is now titled the therapeutic psilocybin and ibogaine research fund at IC 12-21-9-4, with 'ibogaine' defined at IC 12-21-9-1.5. Research funding only; psilocybin remains Schedule I with no patient access program.1
Sources
This entry's status is checked against the primary sources below, and the methodology explains how each entry is graded for confidence.
- 1.iga.in.gov (opens in new tab) · iga.in.gov
- 2.iga.in.gov (opens in new tab) · iga.in.gov
This entry is for information only and is not legal or medical advice. Laws change, and enforcement can differ from the letter of the law, so check the current position against the primary sources above before relying on it.
Changes to this record
3 changes on file, the latest on . Show allHide
Every change we have made to this record, dated, corrections included. Nothing changes silently.
Indiana's psilocybin research fund is funded at $300,000 a year, $600,000 over the two-year budget, and the money comes from the state's opioid settlement account rather than general tax revenue. The amount and its source are now recorded from the budget act itself.
Indiana's research fund was paid for by the biennial state budget, not by the standalone bill the entry credited, and the fund now covers ibogaine as well as psilocybin. Corrected from the legislature's own records.
Indiana had been marked mixed. The only thing the state has enacted is a research fund, which pays for studies and opens no route for patients, so the status is corrected to illegal.
Psilocybin Media Group. "Indiana: psilocybin legal status." The Psilocybin Record, accession US-IN-001, version of 23 Aug 2026. https://psilocybinlegalization.com/record/indiana