The Psilocybin Record
Record / Aug 2026 / Clinical trials

Psilocybin clinical trials

Could you join one? The honest answer first: most of the 327 registered trials are not taking new participants. 132 of them are in the recruiting stage, and your condition is the fastest way to search them. Trial starts have grown roughly seven-fold since 2019.

Sources: ClinicalTrials.gov, EU CTIS, and ISRCTN · updated 21 Aug 2026 · 327 records

Registry data is reported by sponsors and shown as filed.

ClinicalTrials.gov data courtesy of the U.S. National Library of Medicine.

Where the trials run

60 places host psilocybin trials. Every place links to its legal record.

Show all 60 places

Recruiting now

The recruiting stage holds 132 trials across 17 countries: 94 are enrolling now, 32 are not yet recruiting, and 6 enroll by invitation only. 116 of them name a study contact on the record.

Recruiting trials, and how to join →

Trial eligibility is determined solely by each study team. Verify details on the official registry record before acting.

Find a trial

Filter by condition, status, country, and stage. Each title opens the trial’s own registry page, where the eligibility rules are spelled out in full.

Depression

120 trials · 44 recruiting
Does it work?Not yet recruiting
Group PACBT for Depression
NCT07566104Phase 2n=30United Statesupdated May 2026

Ages 21 to 60all sexespatients only

PTSD & trauma

22 trials · 11 recruiting
Does it work?Not yet recruiting
Psilocybin-Assisted Therapy
NCT07332143Phase 2n=150United Statesupdated May 2026

Ages 18 and upall sexespatients onlystudy contact listed

Safety & dosingRecruiting
Psilocybin for Prolonged Grief Disorder
NCT06724289Early phase 1n=12United Statesupdated Jun 2026

Ages 18 to 65all sexeshealthy volunteers acceptedstudy contact listed

Addiction

43 trials · 21 recruiting
Does it work?Recruiting
Wellcome Leap Psilocybin for OUD
NCT06786325Phase 2n=36United Statesupdated Oct 2025

Ages 18 to 60all sexespatients onlystudy contact listed

Does it work?Recruiting
Psilocybin in Cancer Pain Study
NCT06001749Phase 2n=15United Statesupdated Aug 2026

Ages 18 and upall sexespatients onlystudy contact listed

Anxiety

6 trials · 3 recruiting

Cancer & end of life

15 trials · 5 recruiting
Does it work?Recruiting
Psilocybin Therapy in Advanced Cancer
NCT05398484Phase 2 / Phase 3n=200United Statesupdated Dec 2025

Ages 21 to 100all sexespatients onlystudy contact listed

OCD

10 trials · 3 recruiting
Does it work?Not yet recruiting
Psilocybin for Treatment of OCD-2
NCT06992999Phase 1 / Phase 2n=20United Statesupdated May 2026

Ages 18 and upall sexespatients onlystudy contact listed

Eating disorders

8 trials · 2 recruiting

Pain & headache

19 trials · 8 recruiting

Neurological

14 trials · 5 recruiting

Other conditions

13 trials · 7 recruiting
Does it work?Recruiting
Mindfulness-Assisted Psychedelic Therapy
NCT06233344Phase 2n=40United Statesupdated Aug 2026

Ages 25 and upall sexeshealthy volunteers acceptedstudy contact listed

Healthy & mechanism

57 trials · 23 recruiting
Safety & dosingRecruiting
The ENHANCE Study: taVNS and Psilocybin
NCT05866471Phase 1n=108United Statesupdated Jul 2026

Ages 18 to 70all sexeshealthy volunteers acceptedstudy contact listed

Free monthly email

Track changes to psilocybin law.

Clinical trials, bills, and ballot measures across the world: one free email a month with what changed.

New trials and status changes arrive most months. One email when they do.

No spam. Never shared. Unsubscribe anytime. Privacy statement

The law won’t email you. We will.

Common questions

Can I join a trial?
132 trials are in the recruiting stage; 91 of them list sites this register can place. There is no central application: each registry record carries its own eligibility bounds and, where the sponsor filed one, a study contact. 116 of the recruiting trials name a study contact on the record. You contact that team, screening follows, and consent is signed before enrollment. Eligibility is decided by each study team, not here.
Is there a trial for my condition?
Depression is the most studied condition with 120 trials, then addiction with 53, PTSD with 31, and pain with 26. A trial studying more than one condition is counted under each. Every condition is a filter in the register above.
Where are the results?
The register records status, not verdicts. Of 90 completed trials, 19 have results posted to the registry and 5 name a published results paper. A further 57 have papers that cite the trial without reporting its results, and 9 have nothing on record. We count a trial as having results only where the registry says so.
Trials run in places where psilocybin is illegal. How?
Clinical trials operate under research authorizations that are separate from a place’s general law. The atlas above links every place to its legal record on this site.
What do the phases mean?
Phase 1 tests safety and dosing. Phases 2 and 3 test whether the treatment works against comparison groups; 165 trials here are in phase 2 or 3. No psilocybin trial has reached phase 4, the after-approval stage.
Is the field growing?
Trial starts have grown roughly seven-fold since 2019: 8 started in 2019, 58 in 2025, and 66 are already listed for 2026. Start dates include scheduled starts from the registries.
Where does this data come from?
ClinicalTrials.gov, the EU CTIS, and ISRCTN, refreshed on a weekly cadence. ClinicalTrials.gov data is courtesy of the U.S. National Library of Medicine. The corpus behind this page was last updated 21 Aug 2026.

Every figure here is counted from the register at build time. This site makes no medical claims about psilocybin.