1. What the law is
Two paragraphs of Wis. Stat. 961.14(4) do the work: one lists psilocybin, the next psilocin, with penalties set at 961.41. Neither listing has moved through 2026.
Psilocybin is illegal in Wisconsin, where it is classified as a Schedule I controlled substance under the state's Uniform Controlled Substances Act. Wis. Stat. § 961.14(4)(r) lists psilocybin and § 961.14(4)(s) lists psilocin among Schedule I hallucinogenic substances, the most restrictive state schedule. Possession is a criminal offense under Wis. Stat. § 961.41(3g), and manufacture, distribution, or delivery is a felony graded by quantity under § 961.41.
Psilocybin remains a Schedule I controlled substance in Wisconsin as of 2026, and the substance is illegal now; no enacted state law authorizes its possession, use, sale, or supervised administration. Wisconsin has not passed any decriminalization measure or therapeutic-access program. The state legislature considered Senate Bill 727 during the 2023-2024 session, which would have created a medicinal psilocybin treatment fund and a pilot program at the University of Wisconsin-Madison to study the effects of psilocybin on patients with post-traumatic stress disorder; according to the Wisconsin State Legislature's records, that bill failed to pass pursuant to Senate Joint Resolution 1 on April 15, 2024, and never took effect. Because SB 727 was a research-and-study proposal that did not become law, it created no current legal access to psilocybin in Wisconsin.
2. Trials in Wisconsin
Interventional psilocybin trials with at least one site in Wisconsin, as their sponsors filed them with ClinicalTrials.gov, EU CTIS and ISRCTN. Each row links to the registry record, which sets out who may take part.
Recruiting or opening counts trials recruiting now, not yet recruiting, or enrolling by invitation. Closed counts trials terminated, suspended, withdrawn or left unverified by their sponsors.
| Registry ID | Trial | Phase | Sponsor | Status | Start date |
|---|---|---|---|---|---|
| NCT06692192 | The RECAP2 Study: Midazolam and Psilocybin (opens in new tab)Recruiting at UW School of Medicine and Public Health, Madison | Phase Phase 1 | Sponsor University of Wisconsin, Madison | Status Recruiting | Start date |
| NCT05866471 | The ENHANCE Study: taVNS and Psilocybin (opens in new tab)Recruiting at University of Wisconsin - Madison | Phase Phase 1 | Sponsor University of Wisconsin, Madison | Status Recruiting | Start date |
| NCT04161066 | Adjunctive Effects of Psilocybin and a Formulation of Buprenorphine (opens in new tab)Recruiting at University of Wisconsin, Madison | Phase Phase 1 | Sponsor University of Wisconsin, Madison | Status Recruiting | Start date |
| NCT07360301 | Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study (opens in new tab)Site at University of Wisconsin, Madison | Phase Phase 1 | Sponsor University of Wisconsin, Madison | Status Not yet recruiting | Start date |
| NCT05592379 | Consciousness, Psilocybin, and Well-Being (opens in new tab)Site at University of Wisconsin Hospital and Clinics, Madison | Phase Phase 1 | Sponsor University of Wisconsin, Madison | Status Completed | Start date |
| NCT05467761 | Bioavailability Study of Psilocybin in Normal Adults (opens in new tab)Site at University of Wisconsin, Madison | Phase Phase 1 | Sponsor University of Wisconsin, Madison | Status Withdrawn | Start date |
| NCT05322954 | Study of the Safety and Feasibility of Psilocybin in Adults With Methamphetamine Use Disorder (opens in new tab)Site at University of Wisconsin, Madison | Phase Phase 1 | Sponsor University of Wisconsin, Madison | Status Terminated | Start date |
| NCT04842045 | Pilot RECAP Study in Healthy Volunteers (opens in new tab)Site at UWHealth, 600 Highland Avenue, Madison | Phase Phase 1 | Sponsor University of Wisconsin, Madison | Status Completed | Start date |
| NCT03866174 | A Study of Psilocybin for Major Depressive Disorder (MDD) (opens in new tab)Site at University of Wisconsin - Madison | Phase Phase 2 | Sponsor Usona Institute | Status Completed | Start date |
| NCT02163707 | UW Psilocybin Pharmacokinetics Study (opens in new tab)Site at University of Wisconsin, School of Pharmacy, Madison | Phase Phase 1 | Sponsor University of Wisconsin, Madison | Status Completed | Start date |
ClinicalTrials.gov data courtesy of the U.S. National Library of Medicine.
3. History
The legal events behind this entry, dated and oldest first. Our own reviews and corrections are listed under Changes to this record.
Senate Bill 727 introduced, proposing a medicinal psilocybin treatment fund and a UW-Madison pilot program studying psilocybin for treatment-resistant PTSD; it advanced no scheduling or access changes, running through 2024.
Senate Bill 727 failed to pass pursuant to Senate Joint Resolution 1, leaving psilocybin's Schedule I status unchanged.
Psilocybin and psilocin remain Schedule I controlled substances under Wis. Stat. § 961.14(4)(r)-(s); no reform legislation has been enacted.
4. Proposed laws
No proposed law is on file in Wisconsin that would change this entry, as of the 18 Aug 2026 review.
5. Common questions
Is psilocybin legal in Wisconsin?
No. Psilocybin is illegal in Wisconsin. It is a Schedule I controlled substance under Wis. Stat. § 961.14(4)(r), and psilocin is listed at § 961.14(4)(s). The state has enacted no decriminalization or therapeutic-access law.
What is the penalty for psilocybin possession in Wisconsin?
Under Wis. Stat. § 961.41(3g), possession of psilocin or psilocybin is a criminal offense; a first conviction is a misdemeanor punishable by up to one year in county jail, a fine of up to $5,000, or both, and a second or subsequent offense is a Class I felony. Manufacture, distribution, or delivery is charged as a felony graded by quantity under § 961.41.
Did Wisconsin's Senate Bill 727 legalize psilocybin?
No. SB 727 (2023-2024) proposed a treatment fund and a University of Wisconsin-Madison pilot program to study psilocybin for PTSD, but according to the Wisconsin State Legislature it failed to pass on April 15, 2024 and never became law. It created no legal access to psilocybin.
Has Wisconsin decriminalized psilocybin?
No. Wisconsin has enacted no statewide or local measure decriminalizing or deprioritizing enforcement against psilocybin. It remains a Schedule I controlled substance under Wis. Stat. § 961.14, and possession and distribution remain enforceable criminal offenses under § 961.41.
Are magic mushrooms ("shrooms") legal in Wisconsin?
"Magic mushrooms" and "shrooms" are common names for fungi that contain psilocybin, and this entry states the law on psilocybin itself, which some laws treat separately from the fungus. Psilocybin is illegal in Wisconsin.
Read the law
Wis. Stat. § 961.14(4)(r) (Schedule I: Psilocybin) and § 961.14(4)(s) (Schedule I: Psilocin); penalties at § 961.41 reference ‘psilocin and psilocybin’1
Sources
This entry's status is checked against the primary sources below, and the methodology explains how each entry is graded for confidence.
- 1.docs.legis.wisconsin.gov (opens in new tab) · docs.legis.wisconsin.gov
- 2.docs.legis.wisconsin.gov (opens in new tab) · docs.legis.wisconsin.gov
This entry is for information only and is not legal or medical advice. Laws change, and enforcement can differ from the letter of the law, so check the current position against the primary sources above before relying on it.
Changes to this record
Nothing has needed correcting or updating since this record first published.
Psilocybin Media Group. "Wisconsin: psilocybin legal status." The Psilocybin Record, accession US-WI-001, version of 23 Aug 2026. https://psilocybinlegalization.com/record/wisconsin