1. What the law is
The 2026 session produced a psychedelics law that never mentions psilocybin. The Oklahoma Breakthrough Therapy Act, HB 3834, signed May 12, 2026 and effective November 1, 2026, builds a clinical-trial framework for ibogaine alone. No psilocybin bill advanced in that session, and psilocybin is illegal in the state.
Psilocybin is illegal in Oklahoma. It is classified as a Schedule I controlled substance under the Oklahoma Uniform Controlled Dangerous Substances Act (63 O.S. § 2-204), which carries criminal penalties for possession, manufacture, and distribution. No Oklahoma statute authorizes the personal, therapeutic, or commercial use of psilocybin.
Psilocybin remains a Schedule I controlled substance in Oklahoma with no current legal pathway to access. A 2024 measure, HB 3414, would have decriminalized low-level psilocybin possession and funded research; it passed the Oklahoma House of Representatives but died without becoming law, and no successor advanced in the 2026 session. The state's only psychedelic legislation enacted to date, the Oklahoma Breakthrough Therapy Act (HB 3834), was signed by Governor Kevin Stitt on May 12, 2026, and takes effect November 1, 2026, but it establishes a clinical-trial framework for ibogaine only and does not change the legal status of psilocybin. A related measure, HB 4293, would direct ibogaine research at state universities. None of these laws creates legal access to psilocybin, which continues to be prohibited under state law.
2. Trials in Oklahoma
Interventional psilocybin trials with at least one site in Oklahoma, as their sponsors filed them with ClinicalTrials.gov, EU CTIS and ISRCTN. Each row links to the registry record, which sets out who may take part.
Recruiting or opening counts trials recruiting now, not yet recruiting, or enrolling by invitation. Closed counts trials terminated, suspended, withdrawn or left unverified by their sponsors.
| Registry ID | Trial | Phase | Sponsor | Status | Start date |
|---|---|---|---|---|---|
| NCT06793397 | A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder (opens in new tab)Site at SP Research PLLC, Oklahoma City | Phase Phase 3 | Sponsor Cybin IRL Limited | Status Recruiting | Start date |
| NCT05624268 | Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD (opens in new tab)Site at Rivus Wellness & Research Institute, Oklahoma City | Phase Phase 3 | Sponsor COMPASS Pathways | Status Completed | Start date |
ClinicalTrials.gov data courtesy of the U.S. National Library of Medicine.
3. History
The legal events behind this entry, dated and oldest first. Our own reviews and corrections are listed under Changes to this record.
HB 3414, which would have decriminalized low-level psilocybin possession and funded research, passed the Oklahoma House of Representatives but failed to become law.
Governor Kevin Stitt signed HB 3834, the Oklahoma Breakthrough Therapy Act, creating a clinical-trial framework for ibogaine only; it does not affect psilocybin's status.
HB 3834 takes effect (ibogaine research framework only).
4. Proposed laws
No psilocybin bill is pending. The two psychedelic measures of the 2026 session are ibogaine bills and neither is now pending: HB 3834, the Oklahoma Breakthrough Therapy Act, was approved by the Governor on 12 May 2026 and takes effect 1 Nov 2026, and HB 4293, the ibogaine Veterans Mental Health Innovation Act, was referred to Rules on 10 Feb 2026 and had no further action. Both statuses were checked 16 Aug 2026 on the Legislature's own bill-information pages. We have not reviewed every bill filed in the session.
5. Common questions
Is psilocybin legal in Oklahoma?
No. Psilocybin is illegal in Oklahoma, where it is classified as a Schedule I controlled substance under the Oklahoma Uniform Controlled Dangerous Substances Act (63 O.S. § 2-204). Possession, manufacture, and distribution carry criminal penalties.
Did the Oklahoma Breakthrough Therapy Act (HB 3834) legalize psilocybin?
No. HB 3834, signed May 12, 2026 and effective November 1, 2026, establishes a clinical-trial framework for ibogaine only. It does not change the legal status of psilocybin, which remains illegal under Oklahoma law.
Is psilocybin decriminalized in Oklahoma?
No. A 2024 bill, HB 3414, sought to decriminalize low-level psilocybin possession but passed only the Oklahoma House and did not become law. There is no current statute decriminalizing psilocybin in Oklahoma.
What is the penalty for psilocybin possession in Oklahoma?
Because psilocybin is a Schedule I controlled substance under the Oklahoma Uniform Controlled Dangerous Substances Act (63 O.S. § 2-204), its possession, manufacture, and distribution are subject to criminal penalties under state law. Specific charges and sentences depend on the conduct and quantity involved.
Are magic mushrooms ("shrooms") legal in Oklahoma?
"Magic mushrooms" and "shrooms" are common names for fungi that contain psilocybin, and this entry states the law on psilocybin itself, which some laws treat separately from the fungus. Psilocybin is illegal in Oklahoma.
Sources
This entry's status is checked against the primary sources below, and the methodology explains how each entry is graded for confidence.
- 1.oklegislature.gov (opens in new tab) · oklegislature.gov
- 2.Marijuana Moment.Marijuana Moment (opens in new tab) · marijuanamoment.net
This entry is for information only and is not legal or medical advice. Laws change, and enforcement can differ from the letter of the law, so check the current position against the primary sources above before relying on it.
Changes to this record
2 changes on file, the latest on . Show allHide
Every change we have made to this record, dated, corrections included. Nothing changes silently.
Oklahoma moves from mixed to illegal. The only psychedelics law enacted in 2026 covers ibogaine, and no psilocybin bill was enacted.
Oklahoma's entry now records the ibogaine Breakthrough Therapy Act as enacted rather than pending, and cites the enrolled text of the act. Psilocybin's status is unchanged.
Psilocybin Media Group. "Oklahoma: psilocybin legal status." The Psilocybin Record, accession US-OK-001, version of 23 Aug 2026. https://psilocybinlegalization.com/record/oklahoma