1. What the law is
Spain draws its line at the front door. Consuming or possessing psilocybin in a public place is an administrative infraction, fined from 601 to 30,000 euros under article 36.16 of Ley Organica 4/2015 on public security, in force since July 2015. Personal consumption and possession are not criminal offenses at all. The criminal code reaches cultivation, supply and trafficking.
2. Trials in Spain
Interventional psilocybin trials with at least one site in Spain, as their sponsors filed them with ClinicalTrials.gov, EU CTIS and ISRCTN. Each row links to the registry record, which sets out who may take part.
Recruiting or opening counts trials recruiting now, not yet recruiting, or enrolling by invitation. Closed counts trials terminated, suspended, withdrawn or left unverified by their sponsors.
| Registry ID | Trial | Phase | Sponsor | Status | Start date |
|---|---|---|---|---|---|
| 2023-505268-12-00 | A Phase III, multicentre, randomised, double-blind, controlled study to investigate the efficacy, safety, and tolerability of two initial administrations of COMP360 in participants with treatment-resistant depression (opens in new tab)Sites in Barcelona, Collado Villalba, Sant Boi De Llobregat | Phase Not stated | Sponsor Compass Pathfinder Limited | Status Authorised | Start date |
| NCT05711940 | Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD (opens in new tab)Sites in Barcelona, Madrid, Sant Boi de Llobregat | Phase Phase 3 | Sponsor COMPASS Pathways | Status Active, not recruiting | Start date |
| NCT03775200 | The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant Depression (opens in new tab)Two sites in Barcelona | Phase Phase 2 | Sponsor COMPASS Pathways | Status Completed | Start date |
| 2025-521690-14-00 | Antidepressant effects of psilocybin in the absence of serotoninergic psychedelic experience: a dimensional functional neuroimaging approach (opens in new tab)Site at Hospital De La Santa Creu I Sant Pau, Barcelona | Phase Not stated | Sponsor Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau | Status Authorised | Start date Not stated |
ClinicalTrials.gov data courtesy of the U.S. National Library of Medicine.
3. History
The legal events behind this entry, dated and oldest first. Our own reviews and corrections are listed under Changes to this record.
Decriminalized status takes effect.
4. Proposed laws
No proposed law is on file in Spain that would change this entry, as of the 11 Aug 2026 review.
5. Common questions
Is psilocybin legal in Spain?
Psilocybin is decriminalized in Spain.
Are magic mushrooms ("shrooms") legal in Spain?
"Magic mushrooms" and "shrooms" are common names for fungi that contain psilocybin, and this entry states the law on psilocybin itself, which some laws treat separately from the fungus. Psilocybin is decriminalized in Spain.
Read the law
Ley Organica 4/2015 de proteccion de la seguridad ciudadana (in force 1 July 2015), article 36.16: consumption or possession of toxic drugs, narcotics or psychotropic substances in public places is a serious administrative infraction, fined from 601 to 30,000 euros. Penal Code article 368 reaches cultivation, supply and trafficking; personal consumption and possession are not criminal offenses.1
Sources
This entry's status is checked against the primary sources below, and the methodology explains how each entry is graded for confidence.
- 1.boe.es (opens in new tab) · boe.es
- 2.boe.es (opens in new tab) · boe.es
This entry is for information only and is not legal or medical advice. Laws change, and enforcement can differ from the letter of the law, so check the current position against the primary sources above before relying on it.
Changes to this record
2 changes on file, the latest on . Show allHide
Every change we have made to this record, dated, corrections included. Nothing changes silently.
Spain's entry no longer calls small quantities legal. It describes the public-place administrative fine under Ley Organica 4/2015 and keeps personal consumption outside the criminal code, now citing the consolidated Penal Code as well.
Spain's status was confirmed at the official gazette: personal possession is not a crime, and consuming or possessing in public is an administrative infraction under article 36.16 of Ley Organica 4/2015.
Psilocybin Media Group. "Spain: psilocybin legal status." The Psilocybin Record, accession ES-001, version of 23 Aug 2026. https://psilocybinlegalization.com/record/spain