Clinical trials

Who makes the psilocybin in a clinical trial?

In roughly 8% of registered psilocybin trials, the name on the drug isn’t the sponsor’s. No index built on sponsors can show that, and ours is one of them.

Analysis · Finding · By Allan Kerr · Checked 9 September 2026

Usona Institute is a nonprofit in Wisconsin, and its psilocybin is the drug given in eleven registered clinical trials it does not sponsor. Filament Health Corp.’s PEX010 is the drug in sixteen, and Filament’s name appears as sponsor of record on one.

Who actually makes the drug?

Across the 328 psilocybin trials in our corpus, 26 carry a compound supplied by someone other than the trial’s sponsor, and seven branded product codes turn up in those records. Six resolve to an owner; the seventh is held, because the sponsor names on the trials carrying it point to more than one legal entity and our rule refuses to choose.

Two words need pinning down. A code belongs to an organization when exactly one company-type sponsor appears among the trials carrying it, which is our own corpus attesting our own corpus with nothing else behind it. “Supplies” means the registry record for that trial carries the organization’s compound and nothing further, which is no evidence of a contract, a payment or a manufacturing arrangement. It is a name in a field.

Trials each organization supplies, against trials it sponsorsPaired horizontal bars for seven organizations, sorted by the gap between the two measures. Filament Health Corp. supplies 16 and sponsors 1; Usona Institute supplies 11 and sponsors 4; Cybin IRL Limited supplies 4 and sponsors 4; TRYP Therapeutics supplies 2 and sponsors 2; Apex Labs Ltd. supplies 1 and sponsors 1; Eleusis Therapeutics supplies 1 and sponsors 1; Wake Network, Inc. supplies 1 and sponsors 1. Denominator 328 registered psilocybin trials, 5 Sep 2026. Supplied means the trial's registry record carries that organization's compound, and nothing further.Who supplies a trial, and who sponsors itRegistered psilocybin trials, of 328 in the corpus, 5 Sep 2026SuppliesSponsorsFilament Health Corp.161Usona Institute114Cybin IRL Limited44TRYP Therapeutics22Apex Labs Ltd.11Eleusis Therapeutics11Wake Network, Inc.11“Supplies” means the trial’s registry record carries that organization’s compound.It is not evidence of a contract, a payment or a manufacturing arrangement.The Psilocybin Record · derived from raw ClinicalTrials.gov, CTIS and ISRCTN records

Five of the seven supply only trials they also sponsor. Two do not. Usona’s eleven supplied trials and its four sponsored ones are disjoint: no trial appears in both.

So why can’t you look it up?

In the intervention field of a ClinicalTrials.gov record, the drug in one of those eleven trials is named like this:

Psilocybin (Usona Institute)

The answer is typed by the sponsor into a field anyone can read, and what does not exist is a way to ask for it. Our own published trials extract carries 47 fields per row, six of which describe the sponsor and none of which describes the product, so you can ask who funded a psilocybin trial six ways and cannot ask what was in the capsule at all. ClinicalTrials.gov, the European Union’s CTIS and the UK’s ISRCTN each record the intervention as free text, where a product name turns up when it turns up at all; in one ISRCTN record that field runs to 8,119 characters.

On 29 April 2026 Red Light Holland Corp. completed its acquisition of Filament Health Corp. by statutory plan of arrangement under British Columbia’s Business Corporations Act, and Filament became a wholly owned subsidiary. The supplier of sixteen trials changed hands, the sponsor strings on those trials stayed exactly as they were, and a sponsor-indexed view of the field recorded nothing at all.

We ran this on ourselves first, and we failed it

Our own merged corpus put Filament at eleven, and it was wrong. Five of the sixteen name PEX010 only in their European record, and our merge kept the American one, which names psilocybin generically, so the product name died inside our pipeline before anything downstream could read it. Re-deriving from the raw files on 1 September 2026 recovered all five, and on 5 September 2026 we changed the merge to keep every record’s intervention names and added a check that fails the corpus build if one goes missing again. All sixteen survive.

The five were pmg-tr-00168 (Brugmann University Hospital), pmg-tr-00181 (Northern Stockholm Psychiatry), pmg-tr-00189 (University Hospital, Ghent), pmg-tr-00291 (Nantes University Hospital) and pmg-tr-00311 (ARQ National Psychotrauma Centre).

Where each candidate supply edge is recorded: the trial’s main registry record, or only a second registry’sSeven stacked horizontal bars, one per product, sorted by size. Of 36 candidate supply edges, 31 are named in the record of the registry our merge picks as the trial's main one, and 5 are named only in a second registry's record, all 5 of those on PEX010. PEX010 (Filament Health Corp.) 16 edges, 5 of them named only in a second registry's record; Usona Institute (named in full) 11 edges, all in the trial's main registry record; CYB003 (Cybin IRL Limited) 4 edges, all in the trial's main registry record; TRYP0082 (TRYP Therapeutics) 2 edges, all in the trial's main registry record; APEX002 (Apex Labs Ltd.) 1 edge, all in the trial's main registry record; ELE101 (Eleusis Therapeutics) 1 edge, all in the trial's main registry record; PSIL428 (Wake Network, Inc.) 1 edge, all in the trial's main registry record. Until 5 Sep 2026 our merge kept one record's intervention names and dropped the rest, so those 5 were lost before anything downstream could read them; the merge keeps every record's names now and all 36 reach the trial row, 5 Sep 2026.Where each supply edge is recorded36 candidate supply edges, by product, 5 Sep 2026In the trial’s main registry recordOnly in a second registry’s recordPEX010Filament Health Corp.5 of 16Usona Institute (named in full)11CYB003Cybin IRL Limited4TRYP0082TRYP Therapeutics2APEX002Apex Labs Ltd.1ELE101Eleusis Therapeutics1PSIL428Wake Network, Inc.15 edges are named only in a second registry’s record. Until 5 Sep 2026 ourmerge kept one record’s intervention names and dropped the rest, so those5 never reached the trial row. It keeps every record’s names now; all 36 do.The Psilocybin Record · derived from raw ClinicalTrials.gov, CTIS and ISRCTN records

Identity is the other half of the difficulty: the name Filament Health Corp. sits on two British Columbia companies, one active on the register and one inactive, and our record has not established which of them signed the April arrangement.

What would make this wrong

A registry record names what a trial intends to give. It never says whether material moved. Of the 328 trials, 292 produce no candidate supply edge at all, and 271 of those name psilocybin with no product name attached, so part of what is measured here is which organizations brand their material. No primary-source verification pass sits behind a single edge, and concentration here may be entirely ordinary: pharmaceutical-grade psilocybin is difficult to make and tightly scheduled, and a few producers serving many academic trials is what an early, heavily regulated supply chain looks like.

What this does not say

None of this speaks to any product’s quality, safety or effect, and nothing changes who is eligible for a trial or how anyone joins one. No organization named here is accused of anything. Every string behind the finding sits in a public registry record, typed there by the trial’s own sponsor. A nonprofit supplying eleven trials is a fact about research infrastructure, two organizations is a thin layer, and 8% is a floor. The question “who made this” has an answer in the record, and no sponsor-indexed view that will return it.

Method

Method. Every figure re-derives from the raw ClinicalTrials.gov, CTIS and ISRCTN records directly, ahead of our merged corpus. A second and independent derivation reads the same wedge back out of our organization tables and agrees with it on every figure quoted here. Snapshot of 5 Sep 2026: 328 trials, corpus digest 188d9c28b77b686cc0d8d24a7818d99d.

Corrections. corrections@psilocybinlegalization.com.

The Psilocybin RecordPsilocybin Media Group
By Allan Kerr · checked 9 September 2026 · corrections to corrections@psilocybinlegalization.com
Next check 5 October 2026